Non-drug efflux function of ABCC5 promotes enzalutamide resistance in castration-resistant prostate cancer via upregulation of P65/AR-V7

Drug resistance is responsible for castration-resistant prostate cancer (CRPC)-associated mortality. While ATP binding cassette subfamily C member 5 (ABCC5) has been reported to regulate multiple drug resistance, its drug-efflux function may not be the main reason underlying resistance to enzalutami...

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Detalles Bibliográficos
Autores principales: Chen, Haojie, Luo, Jia, Chen, Shaojun, Shi, Bowen, Zheng, Xiaocui, Ji, Haiying, Zhang, Xiaoqian, Yin, Yujia, Du, Kun, Ding, Jie, Yu, Yongjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065095/
https://www.ncbi.nlm.nih.gov/pubmed/35504877
http://dx.doi.org/10.1038/s41420-022-00951-4

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