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Alterations in homologous recombination repair genes in prostate cancer brain metastases

Improved survival rates for prostate cancer through more effective therapies have also led to an increase in the diagnosis of metastases to infrequent locations such as the brain. Here we investigate the repertoire of somatic genetic alterations present in brain metastases from 51 patients with pros...

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Detalles Bibliográficos
Autores principales: Rodriguez-Calero, Antonio, Gallon, John, Akhoundova, Dilara, Maletti, Sina, Ferguson, Alison, Cyrta, Joanna, Amstutz, Ursula, Garofoli, Andrea, Paradiso, Viola, Tomlins, Scott A., Hewer, Ekkehard, Genitsch, Vera, Fleischmann, Achim, Vassella, Erik, Rushing, Elisabeth J., Grobholz, Rainer, Fischer, Ingeborg, Jochum, Wolfram, Cathomas, Gieri, Osunkoya, Adeboye O., Bubendorf, Lukas, Moch, Holger, Thalmann, George, Ng, Charlotte K. Y., Gillessen, Silke, Piscuoglio, Salvatore, Rubin, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065149/
https://www.ncbi.nlm.nih.gov/pubmed/35504881
http://dx.doi.org/10.1038/s41467-022-30003-5