CRISPR-Cas9 mediated generation of a conditional poly(A) binding protein nuclear 1 (Pabpn1) mouse model reveals an essential role for hematopoietic stem cells

Poly(A) binding protein nuclear 1 (PABPN1) is known for its role in poly(A) tail addition and regulation of poly(A) tail length. In addition, it has been shown to be involved in alternative polyadenylation (APA). APA is a process regulating differential selection of polyadenylation sites, thereby in...

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Detalles Bibliográficos
Autores principales: Sommerkamp, Pia, Sommerkamp, Alexander C., Zeisberger, Petra, Eiben, Paula Leonie, Narr, Andreas, Korkmaz, Aylin, Przybylla, Adriana, Sohn, Markus, van der Hoeven, Franciscus, Schönig, Kai, Trumpp, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065150/
https://www.ncbi.nlm.nih.gov/pubmed/35504940
http://dx.doi.org/10.1038/s41598-022-11203-x

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