Somatic FOXC1 insertion mutation remodels the immune microenvironment and promotes the progression of childhood acute lymphoblastic leukemia

Acute lymphoblastic leukemia (ALL) is the most common malignant hematological diseases in children. An immunosuppressive microenvironment, particularly regulatory T cell (Treg) infiltration, has been documented to be highly associated with childhood ALL. This present study, based on genetic factors,...

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Detalles Bibliográficos
Autores principales: Wang, Yaping, Ma, Xiaopeng, Huang, Jie, Yang, Xiaoyun, Kang, Meiyun, Sun, Xiaoyan, Li, Huimin, Wu, Yijun, Zhang, Heng, Zhu, Yuting, Xue, Yao, Fang, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065155/
https://www.ncbi.nlm.nih.gov/pubmed/35504885
http://dx.doi.org/10.1038/s41419-022-04873-y

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