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Counterintuitive production of tumor-suppressive secretomes from Oct4- and c-Myc-overexpressing tumor cells and MSCs

Background: Advanced breast cancer frequently metastasizes to bone, but inhibiting tumor progression in chemotherapy may occasionally enhance tumorigenesis. Here, we employed a counterintuitive approach of overexpressing Yamanaka factors (Oct4, c-Myc, Sox2, and Klf4) and examined a conditioned mediu...

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Detalles Bibliográficos
Autores principales: Li, Kexin, Sun, Xun, Zha, Rongrong, Liu, Shengzhi, Feng, Yan, Sano, Tomonori, Aryal, Uma K., Sudo, Akihiro, Li, Bai-Yan, Yokota, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065181/
https://www.ncbi.nlm.nih.gov/pubmed/35547745
http://dx.doi.org/10.7150/thno.70549