Cargando…
The sodium iodide symporter (NIS) as theranostic gene: its emerging role in new imaging modalities and non-viral gene therapy
Cloning of the sodium iodide symporter (NIS) in 1996 has provided an opportunity to use NIS as a powerful theranostic transgene. Novel gene therapy strategies rely on image-guided selective NIS gene transfer in non-thyroidal tumors followed by application of therapeutic radionuclides. This review hi...
Autores principales: | Kitzberger, Carolin, Spellerberg, Rebekka, Morath, Volker, Schwenk, Nathalie, Schmohl, Kathrin A., Schug, Christina, Urnauer, Sarah, Tutter, Mariella, Eiber, Matthias, Schilling, Franz, Weber, Wolfgang A., Ziegler, Sibylle, Bartenstein, Peter, Wagner, Ernst, Nelson, Peter J., Spitzweg, Christine |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065223/ https://www.ncbi.nlm.nih.gov/pubmed/35503582 http://dx.doi.org/10.1186/s13550-022-00888-w |
Ejemplares similares
-
Effective control of tumor growth through spatial and temporal control of theranostic sodium iodide symporter (NIS) gene expression using a heat-inducible gene promoter in engineered mesenchymal stem cells
por: Tutter, Mariella, et al.
Publicado: (2020) -
Taking Advantage of the TGFB1 Biology in Differentiated Thyroid Cancer to Stimulate Sodium Iodide Symporter (NIS)-Mediated Iodide Uptake in Engineered Mesenchymal Stem Cells
por: Han, Yang, et al.
Publicado: (2021) -
SUN-339 External Beam Radiation Therapy Improves TGFB1-Induced Mesenchymal Stem Cell-Mediated NIS Gene (131)I Therapy
por: Schug, Christina, et al.
Publicado: (2019) -
Selective sodium iodide symporter (NIS) genetherapy of glioblastoma mediatedby EGFR-targeted lipopolyplexes
por: Spellerberg, Rebekka, et al.
Publicado: (2021) -
EGFR-targeted nonviral NIS gene transfer for bioimaging and therapy of disseminated colon cancer metastases
por: Urnauer, Sarah, et al.
Publicado: (2017)