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Pathological Relevance of Anti-Hsp70 IgG Autoantibodies in Epidermolysis Bullosa Acquisita
Stress-induced heat shock protein 70 (Hsp70) is a key intra- and extracellular molecular chaperone implicated in autoimmune processes. Highly immunogenic extracellular Hsp70 can activate innate and acquired (adaptive) immune responses driving the generation of anti-Hsp70 autoantibodies that are freq...
Autores principales: | Tukaj, Stefan, Mantej, Jagoda, Sitko, Krzysztof, Zillikens, Detlef, Ludwig, Ralf J., Bieber, Katja, Kasperkiewicz, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065281/ https://www.ncbi.nlm.nih.gov/pubmed/35514963 http://dx.doi.org/10.3389/fimmu.2022.877958 |
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