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Next-generation of selective histone deacetylase inhibitors

Histone deacetylases (HDACs) are clinically validated epigenetic drug targets for cancer treatment. HDACs inhibitors (HDACis) have been successfully applied against a series of cancers. First-generation inhibitors are mainly pan-HDACis that target multiple isoforms which might lead to serious side e...

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Detalles Bibliográficos
Autores principales:	Yang, Feifei, Zhao, Na, Ge, Di, Chen, Yihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065321/ https://www.ncbi.nlm.nih.gov/pubmed/35519364 http://dx.doi.org/10.1039/c9ra02985k

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