IL-9 Producing Tumor-Infiltrating Lymphocytes and Treg Subsets Drive Immune Escape of Tumor Cells in Non-Small Cell Lung Cancer

Although lung cancer is the leading cause of cancer deaths worldwide, the mechanisms how lung cancer cells evade the immune system remain incompletely understood. Here, we discovered IL-9-dependent signaling mechanisms that drive immune evasion in non-small cell lung cancer (NSCLC). We found increas...

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Detalles Bibliográficos
Autores principales: Heim, Lisanne, Yang, Zuqin, Tausche, Patrick, Hohenberger, Katja, Chiriac, Mircea T., Koelle, Julia, Geppert, Carol-Immanuel, Kachler, Katerina, Miksch, Sarah, Graser, Anna, Friedrich, Juliane, Kharwadkar, Rakshin, Rieker, Ralf J., Trufa, Denis I., Sirbu, Horia, Neurath, Markus F., Kaplan, Mark H., Finotto, Susetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065342/
https://www.ncbi.nlm.nih.gov/pubmed/35514957
http://dx.doi.org/10.3389/fimmu.2022.859738

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