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Trimethyl-Chitosan Coated Gold Nanoparticles Enhance Delivery, Cellular Uptake and Gene Silencing Effect of EGFR-siRNA in Breast Cancer Cells

Purpose: Despite the promising therapeutic effects of gene silencing with small interfering RNAs (siRNAs), the challenges associated with delivery of siRNAs to the tumor cells in vivo, has greatly limited its clinical application. To overcome these challenges, we employed gold nanoparticles modified...

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Detalles Bibliográficos
Autores principales:	Baghani, Leila, Noroozi Heris, Niloofar, Khonsari, Fatemeh, Dinarvand, Sajad, Dinarvand, Meshkat, Atyabi, Fatemeh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065351/ https://www.ncbi.nlm.nih.gov/pubmed/35517864 http://dx.doi.org/10.3389/fmolb.2022.871541

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