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Common Presentation of Uncommon Disease: Inflammatory myofibroblastic tumor of the lung, case report

BACKGROUND: Inflammatory myofibroblastic tumor (IMT) of the lung is a rare lung tumor, accounting for 0.7% of all lung tumors. They are usually benign, but can invade surrounding structures, undergo malignant transformation, recur, or even metastasize. CASE REPORT: We report a 44-year-old adult diab...

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Autores principales: Eldaabossi, Safwat, Maghmoul, Lotfi, Lotfy, Elsaid, Antar, Ahmad, Elghoneimy, Yasser, Aljawad, Hameed, Ghoneim, Ayman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065430/
https://www.ncbi.nlm.nih.gov/pubmed/35516792
http://dx.doi.org/10.1016/j.rmcr.2022.101656
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author Eldaabossi, Safwat
Maghmoul, Lotfi
Lotfy, Elsaid
Antar, Ahmad
Elghoneimy, Yasser
Aljawad, Hameed
Ghoneim, Ayman
author_facet Eldaabossi, Safwat
Maghmoul, Lotfi
Lotfy, Elsaid
Antar, Ahmad
Elghoneimy, Yasser
Aljawad, Hameed
Ghoneim, Ayman
author_sort Eldaabossi, Safwat
collection PubMed
description BACKGROUND: Inflammatory myofibroblastic tumor (IMT) of the lung is a rare lung tumor, accounting for 0.7% of all lung tumors. They are usually benign, but can invade surrounding structures, undergo malignant transformation, recur, or even metastasize. CASE REPORT: We report a 44-year-old adult diabetic male from Saudi Arabia who had been suffering from cough with severe sputum and left shoulder pain for 2 weeks. Chest radiography (X-ray and computed tomography (CT)) revealed the presence of a mass lesion in the left lower upper lobe with central cavitation. The diagnosis of inflammatory myofibroblast lung tumor was confirmed by histological and immunohistochemical examination of the CT guided lung biopsy. The patient was successfully treated with surgical resection of the tumor by left limited thoracotomy with safety margin, and IMT was also documented. CONCLUSION: A high degree of suspicion of a solitary pulmonary mass is required for diagnosis and management of an inflammatory myofibroblastic lung tumor. The clinical and radiologic presentation of an inflammatory myofibroblastic tumor is nonspecific and the diagnosis is rarely made before surgical biopsy. Histologic and immunohistochemical examination is usually required to confirm the diagnosis and prevent recurrence.
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spelling pubmed-90654302022-05-04 Common Presentation of Uncommon Disease: Inflammatory myofibroblastic tumor of the lung, case report Eldaabossi, Safwat Maghmoul, Lotfi Lotfy, Elsaid Antar, Ahmad Elghoneimy, Yasser Aljawad, Hameed Ghoneim, Ayman Respir Med Case Rep Case Report BACKGROUND: Inflammatory myofibroblastic tumor (IMT) of the lung is a rare lung tumor, accounting for 0.7% of all lung tumors. They are usually benign, but can invade surrounding structures, undergo malignant transformation, recur, or even metastasize. CASE REPORT: We report a 44-year-old adult diabetic male from Saudi Arabia who had been suffering from cough with severe sputum and left shoulder pain for 2 weeks. Chest radiography (X-ray and computed tomography (CT)) revealed the presence of a mass lesion in the left lower upper lobe with central cavitation. The diagnosis of inflammatory myofibroblast lung tumor was confirmed by histological and immunohistochemical examination of the CT guided lung biopsy. The patient was successfully treated with surgical resection of the tumor by left limited thoracotomy with safety margin, and IMT was also documented. CONCLUSION: A high degree of suspicion of a solitary pulmonary mass is required for diagnosis and management of an inflammatory myofibroblastic lung tumor. The clinical and radiologic presentation of an inflammatory myofibroblastic tumor is nonspecific and the diagnosis is rarely made before surgical biopsy. Histologic and immunohistochemical examination is usually required to confirm the diagnosis and prevent recurrence. Elsevier 2022-04-26 /pmc/articles/PMC9065430/ /pubmed/35516792 http://dx.doi.org/10.1016/j.rmcr.2022.101656 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Eldaabossi, Safwat
Maghmoul, Lotfi
Lotfy, Elsaid
Antar, Ahmad
Elghoneimy, Yasser
Aljawad, Hameed
Ghoneim, Ayman
Common Presentation of Uncommon Disease: Inflammatory myofibroblastic tumor of the lung, case report
title Common Presentation of Uncommon Disease: Inflammatory myofibroblastic tumor of the lung, case report
title_full Common Presentation of Uncommon Disease: Inflammatory myofibroblastic tumor of the lung, case report
title_fullStr Common Presentation of Uncommon Disease: Inflammatory myofibroblastic tumor of the lung, case report
title_full_unstemmed Common Presentation of Uncommon Disease: Inflammatory myofibroblastic tumor of the lung, case report
title_short Common Presentation of Uncommon Disease: Inflammatory myofibroblastic tumor of the lung, case report
title_sort common presentation of uncommon disease: inflammatory myofibroblastic tumor of the lung, case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065430/
https://www.ncbi.nlm.nih.gov/pubmed/35516792
http://dx.doi.org/10.1016/j.rmcr.2022.101656
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