Can ERAP1 and ERAP2 Form Functional Heterodimers? A Structural Dynamics Investigation

Endoplasmic reticulum aminopeptidases 1 and 2 (ERAP1 and ERAP2) play important roles in the generation of antigenic peptides presented by Major Histocompatibility Class I (MHCI) molecules and indirectly regulate adaptive immune responses. Although the discrete function of these enzymes has been exte...

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Detalles Bibliográficos
Autores principales: Papakyriakou, Athanasios, Mpakali, Anastasia, Stratikos, Efstratios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065437/
https://www.ncbi.nlm.nih.gov/pubmed/35514997
http://dx.doi.org/10.3389/fimmu.2022.863529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065437/
https://www.ncbi.nlm.nih.gov/pubmed/35514997
http://dx.doi.org/10.3389/fimmu.2022.863529

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