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Can ERAP1 and ERAP2 Form Functional Heterodimers? A Structural Dynamics Investigation
Endoplasmic reticulum aminopeptidases 1 and 2 (ERAP1 and ERAP2) play important roles in the generation of antigenic peptides presented by Major Histocompatibility Class I (MHCI) molecules and indirectly regulate adaptive immune responses. Although the discrete function of these enzymes has been exte...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065437/ https://www.ncbi.nlm.nih.gov/pubmed/35514997 http://dx.doi.org/10.3389/fimmu.2022.863529 |