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Lipophilic Constituents in Salvia miltiorrhiza Inhibit Activation of the Hepatic Stellate Cells by Suppressing the JAK1/STAT3 Signaling Pathway: A Network Pharmacology Study and Experimental Validation

Liver fibrosis is currently a global health challenge with no approved therapy, with the activation of hepatic stellate cells being a principal factor. Lipophilic constituents in Salvia miltiorrhiza (LS) have been reported to improve liver function and reduce the indicators of liver fibrosis for pat...

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Detalles Bibliográficos
Autores principales: Tang, Ya-Xin, Liu, Mingming, Liu, Long, Zhen, Bo-Rui, Wang, Tian-Tian, Li, Na, Lv, Nanning, Zhu, Zhenyu, Sun, Guoquan, Wang, Xiaobo, Chen, Si
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065469/
https://www.ncbi.nlm.nih.gov/pubmed/35517817
http://dx.doi.org/10.3389/fphar.2022.770344

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