SIRT6 Activator UBCS039 Inhibits Thioacetamide-Induced Hepatic Injury In Vitro and In Vivo

SIRT6 has been reported to have multiple functions in inflammation and metabolism. In the present study, we explored the regulatory effects and mechanisms of SIRT6 in thioacetamide (TAA)-induced mice acute liver failure (ALF) models. The SIRT6 activator UBCS039 was used in this animal and cell exper...

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Detalles Bibliográficos
Autores principales: Jiao, Fangzhou, Zhang, Zongwei, Hu, Hongtu, Zhang, Yongxi, Xiong, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065480/
https://www.ncbi.nlm.nih.gov/pubmed/35517808
http://dx.doi.org/10.3389/fphar.2022.837544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065480/
https://www.ncbi.nlm.nih.gov/pubmed/35517808
http://dx.doi.org/10.3389/fphar.2022.837544

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