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SIRT6 Activator UBCS039 Inhibits Thioacetamide-Induced Hepatic Injury In Vitro and In Vivo
SIRT6 has been reported to have multiple functions in inflammation and metabolism. In the present study, we explored the regulatory effects and mechanisms of SIRT6 in thioacetamide (TAA)-induced mice acute liver failure (ALF) models. The SIRT6 activator UBCS039 was used in this animal and cell exper...
Autores principales: | Jiao, Fangzhou, Zhang, Zongwei, Hu, Hongtu, Zhang, Yongxi, Xiong, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065480/ https://www.ncbi.nlm.nih.gov/pubmed/35517808 http://dx.doi.org/10.3389/fphar.2022.837544 |
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