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Chronic Exposure to the Combination of Cigarette Smoke and Morphine Decreases CD4(+) Regulatory T Cell Numbers by Reprogramming the Treg Cell Transcriptome
There is a high incidence of tobacco use among intravenous opioid drug users. It is well established that opioids and tobacco smoke induce a degree of immune activation, and recent work suggests that the combination of these drugs promotes further activation of the immune system. Our approach involv...
Autores principales: | Shao, Ying, Cornwell, William, Xu, Keman, Kirchhoff, Aaron, Saasoud, Fatma, Lu, Yifan, Jiang, Xiaohua, Criner, Gerard J., Wang, Hong, Rogers, Thomas J., Yang, Xiaofeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065607/ https://www.ncbi.nlm.nih.gov/pubmed/35514978 http://dx.doi.org/10.3389/fimmu.2022.887681 |
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