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Functional inhibition of c-Myc using novel inhibitors identified through “hot spot” targeting
Protein–protein interactions drive various biological processes in healthy as well as disease states. The transcription factor c-Myc plays a crucial role in maintaining cellular homeostasis, and its deregulated expression is linked to various human cancers; therefore, it can be considered a viable t...
Autores principales: | Singh, Ashutosh, Kumar, Prateek, Sarvagalla, Sailu, Bharadwaj, Taniya, Nayak, Namyashree, Coumar, Mohane Selvaraj, Giri, Rajanish, Garg, Neha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065629/ https://www.ncbi.nlm.nih.gov/pubmed/35378126 http://dx.doi.org/10.1016/j.jbc.2022.101898 |
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