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PALMD regulates aortic valve calcification via altered glycolysis and NF-κB–mediated inflammation
Recent genome-wide association and transcriptome-wide association studies have identified an association between the PALMD locus, encoding palmdelphin, a protein involved in myoblast differentiation, and calcific aortic valve disease (CAVD). Nevertheless, the function and underlying mechanisms of PA...
Autores principales: | Wang, Siying, Yu, Hongjiao, Gao, Jun, Chen, Jiaxin, He, Pengcheng, Zhong, Hui, Tan, Xiao, Staines, Katherine A., Macrae, Vicky E., Fu, Xiaodong, Jiang, Lei, Zhu, Dongxing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065630/ https://www.ncbi.nlm.nih.gov/pubmed/35367413 http://dx.doi.org/10.1016/j.jbc.2022.101887 |
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