Cobalt(ii)-catalyzed benzylic oxidations with potassium persulfate in TFA/TFAA

A cobalt-catalyzed C(sp(3))–H oxygenation reaction to furnish aldehyde was herein reported. This transformation demonstrated high chemo-selectivity, and tolerated various methylarenes bearing electron-withdrawing substituents. This reaction provided rapid access to diverse aldehydes form methylarene...

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Detalles Bibliográficos
Autores principales: Li, Tianlei, Li, Jishun, Zhu, Zihao, Pan, Weidong, Wu, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065695/
https://www.ncbi.nlm.nih.gov/pubmed/35515535
http://dx.doi.org/10.1039/c9ra03346g
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author Li, Tianlei
Li, Jishun
Zhu, Zihao
Pan, Weidong
Wu, Song
author_facet Li, Tianlei
Li, Jishun
Zhu, Zihao
Pan, Weidong
Wu, Song
author_sort Li, Tianlei
collection PubMed
description A cobalt-catalyzed C(sp(3))–H oxygenation reaction to furnish aldehyde was herein reported. This transformation demonstrated high chemo-selectivity, and tolerated various methylarenes bearing electron-withdrawing substituents. This reaction provided rapid access to diverse aldehydes form methylarenes. Notably, TFA/TFAA was used for the first time as a mixed solvent in cobalt-catalyzed oxygenation of benzylic methylenes.
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spelling pubmed-90656952022-05-04 Cobalt(ii)-catalyzed benzylic oxidations with potassium persulfate in TFA/TFAA Li, Tianlei Li, Jishun Zhu, Zihao Pan, Weidong Wu, Song RSC Adv Chemistry A cobalt-catalyzed C(sp(3))–H oxygenation reaction to furnish aldehyde was herein reported. This transformation demonstrated high chemo-selectivity, and tolerated various methylarenes bearing electron-withdrawing substituents. This reaction provided rapid access to diverse aldehydes form methylarenes. Notably, TFA/TFAA was used for the first time as a mixed solvent in cobalt-catalyzed oxygenation of benzylic methylenes. The Royal Society of Chemistry 2019-07-04 /pmc/articles/PMC9065695/ /pubmed/35515535 http://dx.doi.org/10.1039/c9ra03346g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Li, Tianlei
Li, Jishun
Zhu, Zihao
Pan, Weidong
Wu, Song
Cobalt(ii)-catalyzed benzylic oxidations with potassium persulfate in TFA/TFAA
title Cobalt(ii)-catalyzed benzylic oxidations with potassium persulfate in TFA/TFAA
title_full Cobalt(ii)-catalyzed benzylic oxidations with potassium persulfate in TFA/TFAA
title_fullStr Cobalt(ii)-catalyzed benzylic oxidations with potassium persulfate in TFA/TFAA
title_full_unstemmed Cobalt(ii)-catalyzed benzylic oxidations with potassium persulfate in TFA/TFAA
title_short Cobalt(ii)-catalyzed benzylic oxidations with potassium persulfate in TFA/TFAA
title_sort cobalt(ii)-catalyzed benzylic oxidations with potassium persulfate in tfa/tfaa
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065695/
https://www.ncbi.nlm.nih.gov/pubmed/35515535
http://dx.doi.org/10.1039/c9ra03346g
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AT panweidong cobaltiicatalyzedbenzylicoxidationswithpotassiumpersulfateintfatfaa
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