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Outcomes in heart failure patients discharged to skilled nursing facilities with delirium

AIM: Heart failure (HF) outcomes are disproportionately worse in patients discharged to skilled nursing facilities (SNF) as opposed to home. We hypothesized that dementia and delirium were key factors influencing these differences. Our aim was to explore the associations of dementia and delirium wit...

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Autores principales: Lafo, Jacob, Singh, Mriganka, Jiang, Lan, Correia, Stephen, Madrigal, Caroline, Clements, Rachel, Wu, Wen‐Chih, Erqou, Sebhat, Rudolph, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065834/
https://www.ncbi.nlm.nih.gov/pubmed/35293145
http://dx.doi.org/10.1002/ehf2.13895
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author Lafo, Jacob
Singh, Mriganka
Jiang, Lan
Correia, Stephen
Madrigal, Caroline
Clements, Rachel
Wu, Wen‐Chih
Erqou, Sebhat
Rudolph, James L.
author_facet Lafo, Jacob
Singh, Mriganka
Jiang, Lan
Correia, Stephen
Madrigal, Caroline
Clements, Rachel
Wu, Wen‐Chih
Erqou, Sebhat
Rudolph, James L.
author_sort Lafo, Jacob
collection PubMed
description AIM: Heart failure (HF) outcomes are disproportionately worse in patients discharged to skilled nursing facilities (SNF) as opposed to home. We hypothesized that dementia and delirium were key factors influencing these differences. Our aim was to explore the associations of dementia and delirium with risk of hospital readmission and mortality in HF patients discharged to SNF. METHODS AND RESULTS: The study population included Veterans hospitalized for a primary diagnosis of HF and discharged to SNFs between 2010 and 2015. Pre‐existing dementia was identified based on International Classification of Diseases‐9 codes. Delirium was determined using the Minimum Data Set 3.0 Confusion Assessment Method algorithm. Proportional hazard regression analyses were used to model outcomes and were adjusted for covariates of interest. Patients (n = 21 655) were older (77.0 ± 10.5 years) and predominantly male (96.9%). Four groups were created according to presence (+) or absence (−) of dementia and delirium. Relative to the dementia−/delirium− group, the dementia−/delirium+ group was associated with increased 30 day mortality [adjusted hazard ratio (HR) = 2.2, 95% confidence interval (CI) = 1.7, 3.0] and 365 day mortality (adjusted HR = 1.5, 95% CI = 1.3, 1.7). Readmission was highest in the dementia−/delirium+ group after 30 days (HR = 1.2, 95% CI = 1.0, 1.5). In the group with dementia (delirium−/dementia+), 30 day mortality (12.8%; HR = 0.7, 95% CI = 0.7, 0.8) and readmissions (5.3%; HR = 1.0, 95% CI = 0.8, 1.1) were not different relative to the reference group. CONCLUSIONS: Delirium, independent of pre‐existing dementia, confers increased risk of hospital readmission and mortality in HF patients discharged to SNFs. Managing HF after hospitalization is a complex cognitive task and an increased focus on mental status in the acute care setting prior to discharge is needed to improve HF management and transitional care, mitigate adverse outcomes, and reduce healthcare costs.
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spelling pubmed-90658342022-05-04 Outcomes in heart failure patients discharged to skilled nursing facilities with delirium Lafo, Jacob Singh, Mriganka Jiang, Lan Correia, Stephen Madrigal, Caroline Clements, Rachel Wu, Wen‐Chih Erqou, Sebhat Rudolph, James L. ESC Heart Fail Original Articles AIM: Heart failure (HF) outcomes are disproportionately worse in patients discharged to skilled nursing facilities (SNF) as opposed to home. We hypothesized that dementia and delirium were key factors influencing these differences. Our aim was to explore the associations of dementia and delirium with risk of hospital readmission and mortality in HF patients discharged to SNF. METHODS AND RESULTS: The study population included Veterans hospitalized for a primary diagnosis of HF and discharged to SNFs between 2010 and 2015. Pre‐existing dementia was identified based on International Classification of Diseases‐9 codes. Delirium was determined using the Minimum Data Set 3.0 Confusion Assessment Method algorithm. Proportional hazard regression analyses were used to model outcomes and were adjusted for covariates of interest. Patients (n = 21 655) were older (77.0 ± 10.5 years) and predominantly male (96.9%). Four groups were created according to presence (+) or absence (−) of dementia and delirium. Relative to the dementia−/delirium− group, the dementia−/delirium+ group was associated with increased 30 day mortality [adjusted hazard ratio (HR) = 2.2, 95% confidence interval (CI) = 1.7, 3.0] and 365 day mortality (adjusted HR = 1.5, 95% CI = 1.3, 1.7). Readmission was highest in the dementia−/delirium+ group after 30 days (HR = 1.2, 95% CI = 1.0, 1.5). In the group with dementia (delirium−/dementia+), 30 day mortality (12.8%; HR = 0.7, 95% CI = 0.7, 0.8) and readmissions (5.3%; HR = 1.0, 95% CI = 0.8, 1.1) were not different relative to the reference group. CONCLUSIONS: Delirium, independent of pre‐existing dementia, confers increased risk of hospital readmission and mortality in HF patients discharged to SNFs. Managing HF after hospitalization is a complex cognitive task and an increased focus on mental status in the acute care setting prior to discharge is needed to improve HF management and transitional care, mitigate adverse outcomes, and reduce healthcare costs. John Wiley and Sons Inc. 2022-03-15 /pmc/articles/PMC9065834/ /pubmed/35293145 http://dx.doi.org/10.1002/ehf2.13895 Text en © 2022 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology. This article has been contributed to by U.S. Government employees and their work is in the public domain in the USA. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Original Articles
Lafo, Jacob
Singh, Mriganka
Jiang, Lan
Correia, Stephen
Madrigal, Caroline
Clements, Rachel
Wu, Wen‐Chih
Erqou, Sebhat
Rudolph, James L.
Outcomes in heart failure patients discharged to skilled nursing facilities with delirium
title Outcomes in heart failure patients discharged to skilled nursing facilities with delirium
title_full Outcomes in heart failure patients discharged to skilled nursing facilities with delirium
title_fullStr Outcomes in heart failure patients discharged to skilled nursing facilities with delirium
title_full_unstemmed Outcomes in heart failure patients discharged to skilled nursing facilities with delirium
title_short Outcomes in heart failure patients discharged to skilled nursing facilities with delirium
title_sort outcomes in heart failure patients discharged to skilled nursing facilities with delirium
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065834/
https://www.ncbi.nlm.nih.gov/pubmed/35293145
http://dx.doi.org/10.1002/ehf2.13895
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