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Activation of the CREB Coactivator CRTC2 by Aberrant Mitogen Signaling promotes oncogenic functions in HPV16 positive head and neck cancer
Head and neck squamous cell carcinoma (HNSCC) is the 6th most common cancer worldwide and incidence rates are continuing to rise globally. Patients often present with locally advanced disease and a staggering 50% chance of relapse following treatment. Aberrant activation of adaptive response signali...
Autores principales: | Carper, Miranda B., Goel, Saumya, Zhang, Anna M., Damrauer, Jeffrey S., Cohen, Stephanie, Zimmerman, Matthew P., Gentile, Gabrielle M., Parag-Sharma, Kshitij, Murphy, Ryan M., Sato, Kotaro, Nickel, Kwangok P., Kimple, Randall J., Yarbrough, Wendell G., Amelio, Antonio L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065880/ https://www.ncbi.nlm.nih.gov/pubmed/35504112 http://dx.doi.org/10.1016/j.neo.2022.100799 |
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