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Microglia-derived TNF-α inhibiting GABAergic neurons in the anterior lateral bed nucleus of the stria terminalis precipitates visceral hypersensitivity induced by colorectal distension in rats
Irritable bowel syndrome (IBS) is a common and debilitating gastrointestinal disorder that is exacerbated by stress and characterized by abdominal pain. Although microglia in the CNS have been implicated as an important mediator of the stress response, the role of microglia and microglia-GABAergic n...
Autores principales: | Ji, Ning-Ning, Meng, Qing-Xiang, Wang, Ying, Zhou, Zi-Ming, Song, Yu, Hua, Rong, Zhang, Yong-Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065889/ https://www.ncbi.nlm.nih.gov/pubmed/35521065 http://dx.doi.org/10.1016/j.ynstr.2022.100449 |
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