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Central deficiency of IL-6Ra in mice impairs glucose-stimulated insulin secretion
OBJECTIVE: IL-6 is an important contributor to glucose and energy homeostasis through changes in whole-body glucose disposal, insulin sensitivity, food intake and energy expenditure. However, the relative contributions of peripheral versus central IL-6 signaling to these metabolic actions are presen...
Autores principales: | McNeilly, Alison D., Yianakas, Adonis, Gallagher, Jennifer G., Tarlton, Jamie, Ashford, Michael LJ., McCrimmon, Rory J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9065900/ https://www.ncbi.nlm.nih.gov/pubmed/35470093 http://dx.doi.org/10.1016/j.molmet.2022.101488 |
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