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Obesity Exacerbates Coxsackievirus Infection via Lipid-Induced Mitochondrial Reactive Oxygen Species Generation

Coxsackievirus B3 (CVB3) infection causes acute pancreatitis and myocarditis. However, its pathophysiological mechanism is unclear. Here, we investigated how lipid metabolism is associated with exacerbation of CVB3 pathology using high-fat diet (HFD)-induced obese mice. Mice were intraperitoneally i...

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Detalles Bibliográficos
Autores principales: Kim, Seong-Ryeol, Song, Jae-Hyoung, Ahn, Jae-Hee, Jeong, Myeong Seon, Yang, Yoon Mee, Cho, Jaewon, Jeong, Jae-Hyeon, Cha, Younggil, Kim, Kil-Nam, Kim, Hong Pyo, Chang, Sun-Young, Ko, Hyun-Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066006/
https://www.ncbi.nlm.nih.gov/pubmed/35573153
http://dx.doi.org/10.4110/in.2022.22.e19