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In vitro and in vivo evaluation of benzathine foscarnet microcrystals as a potential intravitreal drug depot
Sodium foscarnet is an antiviral drug against cytomegalovirus retinitis, and clinically it is used via frequent intravitreal injection which causes various ocular complications. Here we propose to use benzathine foscarnet in a new salt form with much lower aqueous solubility, and as a potential long...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066022/ https://www.ncbi.nlm.nih.gov/pubmed/35521341 http://dx.doi.org/10.1039/c9ra03070k |