Intra‐epithelial non‐canonical Activin A signaling safeguards prostate progenitor quiescence

The healthy prostate is a relatively quiescent tissue. Yet, prostate epithelium overgrowth is a common condition during aging, associated with urinary dysfunction and tumorigenesis. For over thirty years, TGF‐β ligands have been known to induce cytostasis in a variety of epithelia, but the intracell...

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Detalles Bibliográficos
Autores principales: Cambuli, Francesco, Foletto, Veronica, Alaimo, Alessandro, De Felice, Dario, Gandolfi, Francesco, Palumbieri, Maria Dilia, Zaffagni, Michela, Genovesi, Sacha, Lorenzoni, Marco, Celotti, Martina, Bertossio, Emiliana, Mazzero, Giosuè, Bertossi, Arianna, Bisio, Alessandra, Berardinelli, Francesco, Antoccia, Antonio, Gaspari, Marco, Barbareschi, Mattia, Fiorentino, Michelangelo, Shen, Michael M, Loda, Massimo, Romanel, Alessandro, Lunardi, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066067/
https://www.ncbi.nlm.nih.gov/pubmed/35253958
http://dx.doi.org/10.15252/embr.202154049

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