CEST‐2.2 overexpression alters lipid metabolism and extends longevity of mitochondrial mutants

Mitochondrial dysfunction can either extend or decrease Caenorhabditis elegans lifespan, depending on whether transcriptionally regulated responses can elicit durable stress adaptation to otherwise detrimental lesions. Here, we test the hypothesis that enhanced metabolic flexibility is sufficient to...

Descripción completa

Detalles Bibliográficos
Autores principales: Piazzesi, Antonia, Wang, Yiru, Jackson, Joshua, Wischhof, Lena, Zeisler‐Diehl, Viktoria, Scifo, Enzo, Oganezova, Ina, Hoffmann, Thorben, Gómez Martín, Pablo, Bertan, Fabio, Wrobel, Chester J J, Schroeder, Frank C, Ehninger, Dan, Händler, Kristian, Schultze, Joachim L, Schreiber, Lukas, van Echten‐Deckert, Gerhild, Nicotera, Pierluigi, Bano, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066074/
https://www.ncbi.nlm.nih.gov/pubmed/35297148
http://dx.doi.org/10.15252/embr.202152606

Ejemplares similares

Ejemplares similares