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The role of DNA mismatch repair in immunotherapy of human cancer

DNA mismatch repair (MMR) is an important pathway which helps to maintain genomic stability. Mutations in DNA MMR genes are found to promote cancer initiation and foster tumor progression. Deficiency or inactivation of MMR results in microsatellite instability (MSI) which triggers neoantigen generat...

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Detalles Bibliográficos
Autores principales: He, Yuchen, Zhang, Luyuan, Zhou, Ruoyu, Wang, Yumin, Chen, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066103/
https://www.ncbi.nlm.nih.gov/pubmed/35541922
http://dx.doi.org/10.7150/ijbs.71714