BMI1 promotes spermatogonial stem cell maintenance by epigenetically repressing Wnt10b/β-catenin signaling

The self-renewal of spermatogonial stem cells (SSCs) requires a special microenvironment and is strictly controlled. Previously, we identified BMI1 as a key regulator of spermatogenesis in a knock-out mouse model. However, the mechanisms by which BMI1 regulates SSC maintenance remain largely unknown...

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Detalles Bibliográficos
Autores principales: Yu, Jun, Shen, Cong, Lin, Meng, Chen, Xia, Dai, Xiuliang, Li, Zhiran, Wu, Yunhao, Fu, Yangbo, Lv, Jinxing, Huang, Xiaoyan, Zheng, Bo, Sun, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066105/
https://www.ncbi.nlm.nih.gov/pubmed/35541907
http://dx.doi.org/10.7150/ijbs.70441

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