GRP75-faciliated Mitochondria-associated ER Membrane (MAM) Integrity controls Cisplatin-resistance in Ovarian Cancer Patients

Background: Control of ER-mitochondrial Ca(2+) fluxes is a critical checkpoint to determine cell fate under stress. The 75-kDa glucose-regulated protein (GRP75) is a key tether protein facilitating mitochondria-associated ER membrane (MAM) formation through the IP3R-GRP75-VDAC1 complex. Although GRP...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Jing, Qi, Fangzheng, Su, Huishan, Zhang, Chuanshan, Zhang, Qing, Chen, Ying, Chen, Ping, Su, Linjia, Chen, Yanan, Yang, Yuqi, Chen, Zhesheng, Zhang, Sihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066115/
https://www.ncbi.nlm.nih.gov/pubmed/35541901
http://dx.doi.org/10.7150/ijbs.71571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066115/
https://www.ncbi.nlm.nih.gov/pubmed/35541901
http://dx.doi.org/10.7150/ijbs.71571

Ejemplares similares