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Expeditious synthesis and preliminary antimicrobial activity of deflazacort and its precursors

The synthesis of deflazacort (DFZ) and a preliminary evaluation of its microbial activity against the human pathogens Acinetobacter baumannii and Staphylococcus aureus is herein reported. While DFZ is inactive, one of its synthetic precursors showed a strong antibacterial activity against both Gram-...

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Detalles Bibliográficos
Autores principales: Esposito, Anna, De Gregorio, Eliana, De Fenza, Maria, D'Alonzo, Daniele, Satawani, Anil, Guaragna, Annalisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066171/
https://www.ncbi.nlm.nih.gov/pubmed/35521350
http://dx.doi.org/10.1039/c9ra03673c

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