Inducing Synergistic DNA Damage by TRIP13 and PARP1 Inhibitors Provides a Potential Treatment for Hepatocellular Carcinoma

Thyroid hormone receptor interactor 13 (TRIP13), an AAA-ATPase, participates in the development of many cancers. This study explores the function of TRIP13 and synergistic effects of TRIP13 and PARP1 inhibitors in hepatocellular carcinoma (HCC). The dose-dependent effects of TRIP13 and PARP1 inhibit...

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Detalles Bibliográficos
Autores principales: Xu, Haojun, Ma, Zhijie, Mo, Xiao, Chen, Xiaoli, Xu, Fanggui, Wu, Fubing, Chen, Hongjin, Zhou, Guoren, Xia, Hongping, Zhang, Chengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066198/
https://www.ncbi.nlm.nih.gov/pubmed/35517402
http://dx.doi.org/10.7150/jca.66020

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