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Novel designed azo substituted semi-cyanine fluorescent probe for cytochrome P450 reductase detection and hypoxia imaging in cancer cells

A hypoxia activated fluorescent probe AZO-Cy which contains an azo group conjugated to the electron withdrawing part of the fluorescent dye was synthesized. In the presence of NADH, AZO-Cy displayed high selectivity and sensitivity to cytochrome P450 reductase (CPR) under low p(O(2)). The probe show...

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Detalles Bibliográficos
Autores principales:	Wang, Caiyue, Zhang, Shuping, Huang, Junhai, Cui, Lei, Hu, Jin, Tan, Shaoying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2019
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066356/ https://www.ncbi.nlm.nih.gov/pubmed/35521320 http://dx.doi.org/10.1039/c9ra02741f

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