Aberrant tryptophan metabolism in stromal cells is associated with mesenteric fibrosis in small intestinal neuroendocrine tumors

BACKGROUND: Increased levels of serotonin secretion are associated with mesenteric fibrosis (MF) in small intestinal neuroendocrine tumors (SI-NETs). However, the profibrotic potential of serotonin differs between patients, and in this study, we aimed to gain an understanding of the mechanisms under...

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Detalles Bibliográficos
Autores principales: Blažević, Anela, Iyer, Anand M, van Velthuysen, Marie-Louise F, Hofland, Johannes, van Koestveld, Peter M, Franssen, Gaston J H, Feelders, Richard A, Zajec, Marina, Luider, Theo M, de Herder, Wouter W, Hofland, Leo J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066570/
https://www.ncbi.nlm.nih.gov/pubmed/35275095
http://dx.doi.org/10.1530/EC-22-0020

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