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Insulin-like growth factor role in determining the anti-cancer effect of metformin: RCT in prostate cancer patients

OBJECTIVE: Androgen deprivation therapy (ADT), a principal therapy in patients with prostate cancer, is associated with the development of obesity, insulin resistance, and hyperinsulinemia. Recent evidence indicates that metformin may slow cancer progression and improves survival in prostate cancer...

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Detalles Bibliográficos
Autores principales: Birzniece, Vita, Lam, Teresa, McLean, Mark, Reddy, Navneeta, Shahidipour, Haleh, Hayden, Amy, Gurney, Howard, Stone, Glenn, Hjortebjerg, Rikke, Frystyk, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066575/
https://www.ncbi.nlm.nih.gov/pubmed/35324467
http://dx.doi.org/10.1530/EC-21-0375