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Establishment of atropisomerism in 3-indolyl furanoids: a synthetic, experimental and theoretical perspective
Introduction of axial chirality in bioactive 3-indolyl furanoids has been achieved by systematic alteration of functional groups around the stereogenic axis, keeping in mind that atropisomerically pure analogues may possess different binding affinities and selectivities towards a target protein. The...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066644/ https://www.ncbi.nlm.nih.gov/pubmed/35519481 http://dx.doi.org/10.1039/c9ra05350f |