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Gadd45g is required for timely Sry expression independently of RSPO1 activity

Sex determination in mammals is controlled by the dominance of either pro-testis (SRY-SOX9-FGF9) or pro-ovary (RSPO1-WNT4-FOXL2) genetic pathways during early gonad development in XY and XX embryos, respectively. We have previously shown that early, robust expression of mouse Sry is dependent on the...

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Detalles Bibliográficos
Autores principales:	Warr, Nick, Siggers, Pam, May, Joel, Chalon, Nicolas, Pope, Madeleine, Wells, Sara, Chaboissier, Marie-Christine, Greenfield, Andy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bioscientifica Ltd 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066659/ https://www.ncbi.nlm.nih.gov/pubmed/35315790 http://dx.doi.org/10.1530/REP-21-0443

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