B7-H4 reduction induced by Toxoplasma gondii infection results in dysfunction of decidual dendritic cells by regulating the JAK2/STAT3 pathway

BACKGROUND: Primary infection of Toxoplasma gondii can cause serious abnormal pregnancy outcomes such as miscarriage and stillbirth. Inhibitory molecule B7-H4 is abundantly expressed in dendritic cells (DCs) and plays an important role in maintaining immune tolerance. However, the role of B7-H4 in d...

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Detalles Bibliográficos
Autores principales: Sun, Xinyue, Xie, Hongbing, Zhang, Haixia, Li, Zhidan, Qi, Houbao, Yang, Chunyan, Liu, Xianbing, Ren, Liqin, Jiang, Yuzhu, Hu, Xuemei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066748/
https://www.ncbi.nlm.nih.gov/pubmed/35505420
http://dx.doi.org/10.1186/s13071-022-05263-1

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