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Relapsed boyhood tibia polymicrobial osteomyelitis linked to dermatophytosis: a case report

BACKGROUND: Relapsed childhood polymicrobial osteomyelitis associated with dermatophytosis has not been reported in the literature. CASE PRESENTATION: Here we report on a case of a 45-year-old man who had left tibial osteomyelitis for 29 years, accompanied by skin fungal infection of the ipsilateral...

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Autores principales: Kong, Ping, Ren, Youliang, Yang, Jin, Fu, Wei, Liu, Ziming, Li, Zhengdao, He, Wenbin, Wang, Yunying, Zheng, Zhonghui, Ding, Muliang, Schwarz, Edward M., Deng, Zhongliang, Xie, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066813/
https://www.ncbi.nlm.nih.gov/pubmed/35509041
http://dx.doi.org/10.1186/s12893-022-01600-4
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author Kong, Ping
Ren, Youliang
Yang, Jin
Fu, Wei
Liu, Ziming
Li, Zhengdao
He, Wenbin
Wang, Yunying
Zheng, Zhonghui
Ding, Muliang
Schwarz, Edward M.
Deng, Zhongliang
Xie, Chao
author_facet Kong, Ping
Ren, Youliang
Yang, Jin
Fu, Wei
Liu, Ziming
Li, Zhengdao
He, Wenbin
Wang, Yunying
Zheng, Zhonghui
Ding, Muliang
Schwarz, Edward M.
Deng, Zhongliang
Xie, Chao
author_sort Kong, Ping
collection PubMed
description BACKGROUND: Relapsed childhood polymicrobial osteomyelitis associated with dermatophytosis has not been reported in the literature. CASE PRESENTATION: Here we report on a case of a 45-year-old man who had left tibial osteomyelitis for 29 years, accompanied by skin fungal infection of the ipsilateral heel for 20 years, and underwent a second operation due to recurrence of polymicrobial infection 6 years ago. The patient had a history of injury from a rusty object, which penetrated the anterior skin of the left tibia middle segment causing subsequent bone infection, but was asymptomatic after receiving treatments in 1983. The patient was physically normal until dermatophytosis occurred on the ipsilateral heel skin in 1998. The patient complained that the dermatophytosis was gradually getting worse, and the tibial wound site became itchy, red, and swollen. The left tibial infection resurged in May 2012, leading to the patient receiving debridement and antibiotic treatment. H&E and Gram-stained histology was performed on biopsy specimens of sequestrum and surrounding inflammatory tissue. Tissue culture and microbiology examination confirmed polymicrobial infection with Staphylococcus aureus (S. aureus) and Corynebacterium and a fungus. Additionally, the patient also received potassium permanganate for dermatophytosis when he was admitted into the hospital. CONCLUSIONS: Together with longitudinal follow-up of medical history, surgical findings, histopathological and microbiology culture evidence, we conclude that boyhood tibia polymicrobial osteomyelitis with S. aureus and Corynebacterium occurred in this patient, and the fungal activation of dermatophytosis may have led to osteomyelitis relapse.
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spelling pubmed-90668132022-05-04 Relapsed boyhood tibia polymicrobial osteomyelitis linked to dermatophytosis: a case report Kong, Ping Ren, Youliang Yang, Jin Fu, Wei Liu, Ziming Li, Zhengdao He, Wenbin Wang, Yunying Zheng, Zhonghui Ding, Muliang Schwarz, Edward M. Deng, Zhongliang Xie, Chao BMC Surg Case Report BACKGROUND: Relapsed childhood polymicrobial osteomyelitis associated with dermatophytosis has not been reported in the literature. CASE PRESENTATION: Here we report on a case of a 45-year-old man who had left tibial osteomyelitis for 29 years, accompanied by skin fungal infection of the ipsilateral heel for 20 years, and underwent a second operation due to recurrence of polymicrobial infection 6 years ago. The patient had a history of injury from a rusty object, which penetrated the anterior skin of the left tibia middle segment causing subsequent bone infection, but was asymptomatic after receiving treatments in 1983. The patient was physically normal until dermatophytosis occurred on the ipsilateral heel skin in 1998. The patient complained that the dermatophytosis was gradually getting worse, and the tibial wound site became itchy, red, and swollen. The left tibial infection resurged in May 2012, leading to the patient receiving debridement and antibiotic treatment. H&E and Gram-stained histology was performed on biopsy specimens of sequestrum and surrounding inflammatory tissue. Tissue culture and microbiology examination confirmed polymicrobial infection with Staphylococcus aureus (S. aureus) and Corynebacterium and a fungus. Additionally, the patient also received potassium permanganate for dermatophytosis when he was admitted into the hospital. CONCLUSIONS: Together with longitudinal follow-up of medical history, surgical findings, histopathological and microbiology culture evidence, we conclude that boyhood tibia polymicrobial osteomyelitis with S. aureus and Corynebacterium occurred in this patient, and the fungal activation of dermatophytosis may have led to osteomyelitis relapse. BioMed Central 2022-05-04 /pmc/articles/PMC9066813/ /pubmed/35509041 http://dx.doi.org/10.1186/s12893-022-01600-4 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Kong, Ping
Ren, Youliang
Yang, Jin
Fu, Wei
Liu, Ziming
Li, Zhengdao
He, Wenbin
Wang, Yunying
Zheng, Zhonghui
Ding, Muliang
Schwarz, Edward M.
Deng, Zhongliang
Xie, Chao
Relapsed boyhood tibia polymicrobial osteomyelitis linked to dermatophytosis: a case report
title Relapsed boyhood tibia polymicrobial osteomyelitis linked to dermatophytosis: a case report
title_full Relapsed boyhood tibia polymicrobial osteomyelitis linked to dermatophytosis: a case report
title_fullStr Relapsed boyhood tibia polymicrobial osteomyelitis linked to dermatophytosis: a case report
title_full_unstemmed Relapsed boyhood tibia polymicrobial osteomyelitis linked to dermatophytosis: a case report
title_short Relapsed boyhood tibia polymicrobial osteomyelitis linked to dermatophytosis: a case report
title_sort relapsed boyhood tibia polymicrobial osteomyelitis linked to dermatophytosis: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066813/
https://www.ncbi.nlm.nih.gov/pubmed/35509041
http://dx.doi.org/10.1186/s12893-022-01600-4
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