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CRISPR-Cas12a combination to alleviate the false-positive in loop-mediated isothermal amplification-based diagnosis of Neisseria meningitidis

BACKGROUND: Loop isothermal amplification (LAMP) has recently been proposed as a point-of-care diagnostic tool to detect acute infectious pathogens; however, this technique embeds risk of generating false-positive results. Whereas, with abilities to accurately recognize specific sequence, the CRISPR...

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Detalles Bibliográficos
Autores principales: Trung, Ngo Tat, Son, Le Huu Phuc, Hien, Trinh Xuan, Quyen, Dao Thanh, Bang, Mai Hong, Song, Le Huu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066958/
https://www.ncbi.nlm.nih.gov/pubmed/35508977
http://dx.doi.org/10.1186/s12879-022-07363-w