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Three-dimensional (3D) liver cell models - a tool for bridging the gap between animal studies and clinical trials when screening liver accumulation and toxicity of nanobiomaterials

Despite the exciting properties and wide-reaching applications of nanobiomaterials (NBMs) in human health and medicine, their translation from bench to bedside is slow, with a predominant issue being liver accumulation and toxicity following systemic administration. In vitro 2D cell-based assays and...

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Detalles Bibliográficos
Autores principales: Tutty, Melissa Anne, Movia, Dania, Prina-Mello, Adriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9066991/
https://www.ncbi.nlm.nih.gov/pubmed/35507131
http://dx.doi.org/10.1007/s13346-022-01147-0