RT-PCR/MALDI-TOF Diagnostic Target Performance Reflects Circulating SARS-CoV-2 Variant Diversity in New York City

As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to circulate, multiple variants of concern have emerged. New variants pose challenges for diagnostic platforms because sequence diversity can alter primer/probe-binding sites (PBSs), causing false-negative results. The MassARR...

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Detalles Bibliográficos
Autores principales: Hernandez, Matthew M., Banu, Radhika, Gonzalez-Reiche, Ana S., Gray, Brandon, Shrestha, Paras, Cao, Liyong, Chen, Feng, Shi, Huanzhi, Hanna, Ayman, Ramírez, Juan David, van de Guchte, Adriana, Sebra, Robert, Gitman, Melissa R., Nowak, Michael D., Cordon-Cardo, Carlos, Schutzbank, Ted E., Simon, Viviana, van Bakel, Harm, Sordillo, Emilia Mia, Paniz-Mondolfi, Alberto E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Investigative Pathology 2022
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067105/
https://www.ncbi.nlm.nih.gov/pubmed/35525388
http://dx.doi.org/10.1016/j.jmoldx.2022.04.003

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