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New ligand-binding sites identified in the crystal structures of β-lactoglobulin complexes with desipramine

The homodimeric β-lactoglobulin belongs to the lipocalin family of proteins that transport a wide range of hydrophobic molecules and can be modified by mutagenesis to develop specificity for novel groups of ligands. In this work, new lactoglobulin variants, FAF (I56F/L39A/M107F) and FAW (I56F/L39A/M...

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Detalles Bibliográficos
Autores principales:	Loch, Joanna I., Barciszewski, Jakub, Śliwiak, Joanna, Bonarek, Piotr, Wróbel, Paulina, Pokrywka, Kinga, Shabalin, Ivan G., Minor, Wladek, Jaskolski, Mariusz, Lewiński, Krzysztof
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2022
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067113/ https://www.ncbi.nlm.nih.gov/pubmed/35546795 http://dx.doi.org/10.1107/S2052252522004183

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