Nicotinamide (niacin) supplement increases lipid metabolism and ROS‐induced energy disruption in triple‐negative breast cancer: potential for drug repositioning as an anti‐tumor agent

Metabolic dysregulation is an important hallmark of cancer. Nicotinamide (NAM), a water‐soluble amide form of niacin (vitamin B3), is currently available as a supplement for maintaining general physiologic functions. NAM is a crucial regulator of mitochondrial metabolism and redox reactions. In this...

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Detalles Bibliográficos
Autores principales: Jung, Minsun, Lee, Kyung‐Min, Im, Yebin, Seok, Seung Hyeok, Chung, Hyewon, Kim, Da Young, Han, Dohyun, Lee, Cheng Hyun, Hwang, Eun Hye, Park, Soo Young, Koh, Jiwon, Kim, Bohyun, Nikas, Ilias P., Lee, Hyebin, Hwang, Daehee, Ryu, Han Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067146/
https://www.ncbi.nlm.nih.gov/pubmed/35278276
http://dx.doi.org/10.1002/1878-0261.13209

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