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Quality-of-Life Outcomes in Female Patients With Ileal Conduit or Orthotopic Neobladder Urinary Diversion: 6-Month Results of a Multicenter Prospective Study
Radical cystectomy (RC) often affects patients’ life as this surgery is a traumatic and invasive event for the patients, with drawbacks on their daily, social, working, and sex life. Such changes in the quality of life (QoL) of patients are commonly studied through retrospective clinical evaluations...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067240/ https://www.ncbi.nlm.nih.gov/pubmed/35515136 http://dx.doi.org/10.3389/fonc.2022.855546 |
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author | Siracusano, Salvatore Zaka, Agustina Bassi, Pierfrancesco Gontero, Paolo Mearini, Ettore Imbimbo, Ciro Simonato, Alchiede Dal Moro, Fabrizio Giannarini, Gianluca Valotto, Claudio Montorsi, Francesco Colombo, Renzo Porpiglia, Francesco Bartoletti, Riccardo Vella, Marco Minervini, Andrea Porcaro, Antonio Benito Romantini, Federico Vicentini, Carlo Talamini, Renato Ficarra, Vincenzo Lonardi, Cristina |
author_facet | Siracusano, Salvatore Zaka, Agustina Bassi, Pierfrancesco Gontero, Paolo Mearini, Ettore Imbimbo, Ciro Simonato, Alchiede Dal Moro, Fabrizio Giannarini, Gianluca Valotto, Claudio Montorsi, Francesco Colombo, Renzo Porpiglia, Francesco Bartoletti, Riccardo Vella, Marco Minervini, Andrea Porcaro, Antonio Benito Romantini, Federico Vicentini, Carlo Talamini, Renato Ficarra, Vincenzo Lonardi, Cristina |
author_sort | Siracusano, Salvatore |
collection | PubMed |
description | Radical cystectomy (RC) often affects patients’ life as this surgery is a traumatic and invasive event for the patients, with drawbacks on their daily, social, working, and sex life. Such changes in the quality of life (QoL) of patients are commonly studied through retrospective clinical evaluations and rarely with longitudinal studies. To date, studies focusing on functional outcomes, sexual function, and health-related QoL for female patients are lacking. We evaluated 37 patients using EORTC QLQ-C30 (QLQ-30) and Short-Form 36 (SF-36) questionnaires, before and after surgery, at 3 and 6 months of follow-up. The mean values for the emotional functioning in QLQ-C30 as well as the mental health in SF-36 were significantly higher in the ONB group compared to the IC group at 3 months of follow-up. These differences were not significant at 6 months of follow-up. At 6 months of follow-up, the ONB group showed a higher mean score in the physical and role functioning than the IC group. Although there was a statistically significant age difference at baseline of the two groups, none of the results are correlated with age, as demonstrated by Spearman’s analysis. The ONB seems to represent the most advantageous solution compared to the IC in terms of QOL at the 6-month follow-up. |
format | Online Article Text |
id | pubmed-9067240 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-90672402022-05-04 Quality-of-Life Outcomes in Female Patients With Ileal Conduit or Orthotopic Neobladder Urinary Diversion: 6-Month Results of a Multicenter Prospective Study Siracusano, Salvatore Zaka, Agustina Bassi, Pierfrancesco Gontero, Paolo Mearini, Ettore Imbimbo, Ciro Simonato, Alchiede Dal Moro, Fabrizio Giannarini, Gianluca Valotto, Claudio Montorsi, Francesco Colombo, Renzo Porpiglia, Francesco Bartoletti, Riccardo Vella, Marco Minervini, Andrea Porcaro, Antonio Benito Romantini, Federico Vicentini, Carlo Talamini, Renato Ficarra, Vincenzo Lonardi, Cristina Front Oncol Oncology Radical cystectomy (RC) often affects patients’ life as this surgery is a traumatic and invasive event for the patients, with drawbacks on their daily, social, working, and sex life. Such changes in the quality of life (QoL) of patients are commonly studied through retrospective clinical evaluations and rarely with longitudinal studies. To date, studies focusing on functional outcomes, sexual function, and health-related QoL for female patients are lacking. We evaluated 37 patients using EORTC QLQ-C30 (QLQ-30) and Short-Form 36 (SF-36) questionnaires, before and after surgery, at 3 and 6 months of follow-up. The mean values for the emotional functioning in QLQ-C30 as well as the mental health in SF-36 were significantly higher in the ONB group compared to the IC group at 3 months of follow-up. These differences were not significant at 6 months of follow-up. At 6 months of follow-up, the ONB group showed a higher mean score in the physical and role functioning than the IC group. Although there was a statistically significant age difference at baseline of the two groups, none of the results are correlated with age, as demonstrated by Spearman’s analysis. The ONB seems to represent the most advantageous solution compared to the IC in terms of QOL at the 6-month follow-up. Frontiers Media S.A. 2022-04-12 /pmc/articles/PMC9067240/ /pubmed/35515136 http://dx.doi.org/10.3389/fonc.2022.855546 Text en Copyright © 2022 Siracusano, Zaka, Bassi, Gontero, Mearini, Imbimbo, Simonato, Dal Moro, Giannarini, Valotto, Montorsi, Colombo, Porpiglia, Bartoletti, Vella, Minervini, Porcaro, Romantini, Vicentini, Talamini, Ficarra and Lonardi https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Siracusano, Salvatore Zaka, Agustina Bassi, Pierfrancesco Gontero, Paolo Mearini, Ettore Imbimbo, Ciro Simonato, Alchiede Dal Moro, Fabrizio Giannarini, Gianluca Valotto, Claudio Montorsi, Francesco Colombo, Renzo Porpiglia, Francesco Bartoletti, Riccardo Vella, Marco Minervini, Andrea Porcaro, Antonio Benito Romantini, Federico Vicentini, Carlo Talamini, Renato Ficarra, Vincenzo Lonardi, Cristina Quality-of-Life Outcomes in Female Patients With Ileal Conduit or Orthotopic Neobladder Urinary Diversion: 6-Month Results of a Multicenter Prospective Study |
title | Quality-of-Life Outcomes in Female Patients With Ileal Conduit or Orthotopic Neobladder Urinary Diversion: 6-Month Results of a Multicenter Prospective Study |
title_full | Quality-of-Life Outcomes in Female Patients With Ileal Conduit or Orthotopic Neobladder Urinary Diversion: 6-Month Results of a Multicenter Prospective Study |
title_fullStr | Quality-of-Life Outcomes in Female Patients With Ileal Conduit or Orthotopic Neobladder Urinary Diversion: 6-Month Results of a Multicenter Prospective Study |
title_full_unstemmed | Quality-of-Life Outcomes in Female Patients With Ileal Conduit or Orthotopic Neobladder Urinary Diversion: 6-Month Results of a Multicenter Prospective Study |
title_short | Quality-of-Life Outcomes in Female Patients With Ileal Conduit or Orthotopic Neobladder Urinary Diversion: 6-Month Results of a Multicenter Prospective Study |
title_sort | quality-of-life outcomes in female patients with ileal conduit or orthotopic neobladder urinary diversion: 6-month results of a multicenter prospective study |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067240/ https://www.ncbi.nlm.nih.gov/pubmed/35515136 http://dx.doi.org/10.3389/fonc.2022.855546 |
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