Cargando…

Quality-of-Life Outcomes in Female Patients With Ileal Conduit or Orthotopic Neobladder Urinary Diversion: 6-Month Results of a Multicenter Prospective Study

Radical cystectomy (RC) often affects patients’ life as this surgery is a traumatic and invasive event for the patients, with drawbacks on their daily, social, working, and sex life. Such changes in the quality of life (QoL) of patients are commonly studied through retrospective clinical evaluations...

Descripción completa

Detalles Bibliográficos
Autores principales: Siracusano, Salvatore, Zaka, Agustina, Bassi, Pierfrancesco, Gontero, Paolo, Mearini, Ettore, Imbimbo, Ciro, Simonato, Alchiede, Dal Moro, Fabrizio, Giannarini, Gianluca, Valotto, Claudio, Montorsi, Francesco, Colombo, Renzo, Porpiglia, Francesco, Bartoletti, Riccardo, Vella, Marco, Minervini, Andrea, Porcaro, Antonio Benito, Romantini, Federico, Vicentini, Carlo, Talamini, Renato, Ficarra, Vincenzo, Lonardi, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067240/
https://www.ncbi.nlm.nih.gov/pubmed/35515136
http://dx.doi.org/10.3389/fonc.2022.855546
_version_ 1784699965656793088
author Siracusano, Salvatore
Zaka, Agustina
Bassi, Pierfrancesco
Gontero, Paolo
Mearini, Ettore
Imbimbo, Ciro
Simonato, Alchiede
Dal Moro, Fabrizio
Giannarini, Gianluca
Valotto, Claudio
Montorsi, Francesco
Colombo, Renzo
Porpiglia, Francesco
Bartoletti, Riccardo
Vella, Marco
Minervini, Andrea
Porcaro, Antonio Benito
Romantini, Federico
Vicentini, Carlo
Talamini, Renato
Ficarra, Vincenzo
Lonardi, Cristina
author_facet Siracusano, Salvatore
Zaka, Agustina
Bassi, Pierfrancesco
Gontero, Paolo
Mearini, Ettore
Imbimbo, Ciro
Simonato, Alchiede
Dal Moro, Fabrizio
Giannarini, Gianluca
Valotto, Claudio
Montorsi, Francesco
Colombo, Renzo
Porpiglia, Francesco
Bartoletti, Riccardo
Vella, Marco
Minervini, Andrea
Porcaro, Antonio Benito
Romantini, Federico
Vicentini, Carlo
Talamini, Renato
Ficarra, Vincenzo
Lonardi, Cristina
author_sort Siracusano, Salvatore
collection PubMed
description Radical cystectomy (RC) often affects patients’ life as this surgery is a traumatic and invasive event for the patients, with drawbacks on their daily, social, working, and sex life. Such changes in the quality of life (QoL) of patients are commonly studied through retrospective clinical evaluations and rarely with longitudinal studies. To date, studies focusing on functional outcomes, sexual function, and health-related QoL for female patients are lacking. We evaluated 37 patients using EORTC QLQ-C30 (QLQ-30) and Short-Form 36 (SF-36) questionnaires, before and after surgery, at 3 and 6 months of follow-up. The mean values for the emotional functioning in QLQ-C30 as well as the mental health in SF-36 were significantly higher in the ONB group compared to the IC group at 3 months of follow-up. These differences were not significant at 6 months of follow-up. At 6 months of follow-up, the ONB group showed a higher mean score in the physical and role functioning than the IC group. Although there was a statistically significant age difference at baseline of the two groups, none of the results are correlated with age, as demonstrated by Spearman’s analysis. The ONB seems to represent the most advantageous solution compared to the IC in terms of QOL at the 6-month follow-up.
format Online
Article
Text
id pubmed-9067240
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-90672402022-05-04 Quality-of-Life Outcomes in Female Patients With Ileal Conduit or Orthotopic Neobladder Urinary Diversion: 6-Month Results of a Multicenter Prospective Study Siracusano, Salvatore Zaka, Agustina Bassi, Pierfrancesco Gontero, Paolo Mearini, Ettore Imbimbo, Ciro Simonato, Alchiede Dal Moro, Fabrizio Giannarini, Gianluca Valotto, Claudio Montorsi, Francesco Colombo, Renzo Porpiglia, Francesco Bartoletti, Riccardo Vella, Marco Minervini, Andrea Porcaro, Antonio Benito Romantini, Federico Vicentini, Carlo Talamini, Renato Ficarra, Vincenzo Lonardi, Cristina Front Oncol Oncology Radical cystectomy (RC) often affects patients’ life as this surgery is a traumatic and invasive event for the patients, with drawbacks on their daily, social, working, and sex life. Such changes in the quality of life (QoL) of patients are commonly studied through retrospective clinical evaluations and rarely with longitudinal studies. To date, studies focusing on functional outcomes, sexual function, and health-related QoL for female patients are lacking. We evaluated 37 patients using EORTC QLQ-C30 (QLQ-30) and Short-Form 36 (SF-36) questionnaires, before and after surgery, at 3 and 6 months of follow-up. The mean values for the emotional functioning in QLQ-C30 as well as the mental health in SF-36 were significantly higher in the ONB group compared to the IC group at 3 months of follow-up. These differences were not significant at 6 months of follow-up. At 6 months of follow-up, the ONB group showed a higher mean score in the physical and role functioning than the IC group. Although there was a statistically significant age difference at baseline of the two groups, none of the results are correlated with age, as demonstrated by Spearman’s analysis. The ONB seems to represent the most advantageous solution compared to the IC in terms of QOL at the 6-month follow-up. Frontiers Media S.A. 2022-04-12 /pmc/articles/PMC9067240/ /pubmed/35515136 http://dx.doi.org/10.3389/fonc.2022.855546 Text en Copyright © 2022 Siracusano, Zaka, Bassi, Gontero, Mearini, Imbimbo, Simonato, Dal Moro, Giannarini, Valotto, Montorsi, Colombo, Porpiglia, Bartoletti, Vella, Minervini, Porcaro, Romantini, Vicentini, Talamini, Ficarra and Lonardi https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Siracusano, Salvatore
Zaka, Agustina
Bassi, Pierfrancesco
Gontero, Paolo
Mearini, Ettore
Imbimbo, Ciro
Simonato, Alchiede
Dal Moro, Fabrizio
Giannarini, Gianluca
Valotto, Claudio
Montorsi, Francesco
Colombo, Renzo
Porpiglia, Francesco
Bartoletti, Riccardo
Vella, Marco
Minervini, Andrea
Porcaro, Antonio Benito
Romantini, Federico
Vicentini, Carlo
Talamini, Renato
Ficarra, Vincenzo
Lonardi, Cristina
Quality-of-Life Outcomes in Female Patients With Ileal Conduit or Orthotopic Neobladder Urinary Diversion: 6-Month Results of a Multicenter Prospective Study
title Quality-of-Life Outcomes in Female Patients With Ileal Conduit or Orthotopic Neobladder Urinary Diversion: 6-Month Results of a Multicenter Prospective Study
title_full Quality-of-Life Outcomes in Female Patients With Ileal Conduit or Orthotopic Neobladder Urinary Diversion: 6-Month Results of a Multicenter Prospective Study
title_fullStr Quality-of-Life Outcomes in Female Patients With Ileal Conduit or Orthotopic Neobladder Urinary Diversion: 6-Month Results of a Multicenter Prospective Study
title_full_unstemmed Quality-of-Life Outcomes in Female Patients With Ileal Conduit or Orthotopic Neobladder Urinary Diversion: 6-Month Results of a Multicenter Prospective Study
title_short Quality-of-Life Outcomes in Female Patients With Ileal Conduit or Orthotopic Neobladder Urinary Diversion: 6-Month Results of a Multicenter Prospective Study
title_sort quality-of-life outcomes in female patients with ileal conduit or orthotopic neobladder urinary diversion: 6-month results of a multicenter prospective study
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067240/
https://www.ncbi.nlm.nih.gov/pubmed/35515136
http://dx.doi.org/10.3389/fonc.2022.855546
work_keys_str_mv AT siracusanosalvatore qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT zakaagustina qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT bassipierfrancesco qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT gonteropaolo qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT meariniettore qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT imbimbociro qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT simonatoalchiede qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT dalmorofabrizio qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT giannarinigianluca qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT valottoclaudio qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT montorsifrancesco qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT colomborenzo qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT porpigliafrancesco qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT bartolettiriccardo qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT vellamarco qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT minerviniandrea qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT porcaroantoniobenito qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT romantinifederico qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT vicentinicarlo qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT talaminirenato qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT ficarravincenzo qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy
AT lonardicristina qualityoflifeoutcomesinfemalepatientswithilealconduitororthotopicneobladderurinarydiversion6monthresultsofamulticenterprospectivestudy