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Biochemical and crystallization analysis of the CENP-SX–DNA complex

The CENP-SX (MHF) complex is a conserved histone-fold protein complex that is involved in chromosome segregation and DNA repair. It can bind to DNA on its own as well as in complex with other proteins such as CENP-TW and FANCM to recognize specific substrates. CENP-SX binds nonspecifically to dsDNA,...

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Detalles Bibliográficos
Autores principales: Ito, Sho, Nishino, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067375/
https://www.ncbi.nlm.nih.gov/pubmed/35506764
http://dx.doi.org/10.1107/S2053230X22003843