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Noncanonical imprinting sustains embryonic development and restrains placental overgrowth

Genomic imprinting regulates parental origin-dependent monoallelic gene expression. It is mediated by either germline differential methylation of DNA (canonical imprinting) or oocyte-derived H3K27me3 (noncanonical imprinting) in mice. Depletion of Eed, an essential component of Polycomb repressive c...

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Detalles Bibliográficos
Autores principales: Matoba, Shogo, Kozuka, Chisayo, Miura, Kento, Inoue, Kimiko, Kumon, Mami, Hayashi, Ryoya, Ohhata, Tatsuya, Ogura, Atsuo, Inoue, Azusa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067403/
https://www.ncbi.nlm.nih.gov/pubmed/35483741
http://dx.doi.org/10.1101/gad.349390.122