Cargando…

Biglycan as a potential regulator of tumorgenicity and immunogenicity in K-RAS-transformed cells

The extracellular matrix component biglycan (BGN) plays an essential role in various physiological and pathophysiological processes. A deficient BGN expression associated with reduced immunogenicity was found in HER-2/neu-overexpressing cells. To determine whether BGN is suppressed by oncogene-drive...

Descripción completa

Detalles Bibliográficos
Autores principales:	Subbarayan, Karthikeyan, Massa, Chiara, Leisz, Sandra, Steven, André, Bethmann, Daniel, Biehl, Katharina, Wickenhauser, Claudia, Seliger, Barbara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067524/ https://www.ncbi.nlm.nih.gov/pubmed/35529675 http://dx.doi.org/10.1080/2162402X.2022.2069214

Ejemplares similares

Biglycan as a mediator of proinflammatory response and target for MDS and sAML therapy
por: Vaxevanis, Christoforos K., et al.
Publicado: (2022)

Identification of a novel miR‐21‐3p/TGF‐β signaling‐driven immune escape via the MHC class I/biglycan axis in tumor cells
por: Subbarayan, Karthikeyan, et al.
Publicado: (2021)

Immune Interaction Map of Human SARS-CoV-2 Target Genes: Implications for Therapeutic Avenues
por: Subbarayan, Karthikeyan, et al.
Publicado: (2021)

Immune Escape Mechanisms and Their Clinical Relevance in Head and Neck Squamous Cell Carcinoma
por: Seliger, Barbara, et al.
Publicado: (2020)

MBRS-22. SIGNIFICANCE OF RNF213 IN TUMORGENICITY OF MEDULLOBLASTOMA
por: Mineharu, Yohei, et al.
Publicado: (2020)

Hypoxia-mediated alterations and their role in the HER-2/neuregulated CREB status and localization
por: Steven, André, et al.
Publicado: (2016)

Linking CREB function with altered metabolism in murine fibroblast-based model cell lines
por: Steven, André, et al.
Publicado: (2017)

Targeting Asparagine Synthetase in Tumorgenicity Using Patient-Derived Tumor-Initiating Cells
por: Nishikawa, Gen, et al.
Publicado: (2022)

Correlation of the tumor escape phenotype with loss of PRELP expression in melanoma
por: Schäfer, Helene, et al.
Publicado: (2023)

Induction of pulmonary HLA-G expression by SARS-CoV-2 infection
por: Seliger, Barbara, et al.
Publicado: (2022)

Tumor Microenvironment, HLA Class I and APM Expression in HPV-Negative Oral Squamous Cell Carcinoma
por: Wickenhauser, Claudia, et al.
Publicado: (2021)

Deletion of the thrombin cleavage domain of osteopontin mediates breast cancer cell adhesion, proteolytic activity, tumorgenicity, and metastasis
por: Beausoleil, Michel S, et al.
Publicado: (2011)

The Role of Decorin and Biglycan Signaling in Tumorigenesis
por: Diehl, Valentina, et al.
Publicado: (2021)

Biglycan regulates bone development and regeneration
por: Shainer, Reut, et al.
Publicado: (2023)

Breast cancer dataset with biomarker Biglycan
por: Silva Neto, Pedro Clarindo da, et al.
Publicado: (2023)

VHL-dependent alterations in the secretome of renal cell carcinoma: Association with immune cell response?
por: Stehle, Franziska, et al.
Publicado: (2015)

Resistance to ursodeoxycholic acid-induced growth arrest can also result in resistance to deoxycholic acid-induced apoptosis and increased tumorgenicity
por: Powell, Ashley A, et al.
Publicado: (2006)

Identification of microRNAs Targeting the Transporter Associated with Antigen Processing TAP1 in Melanoma
por: Lazaridou, Maria-Filothei, et al.
Publicado: (2020)

Expression and the Prognostic Value of Biglycan in Gastric Cancer
por: Hu, Sizhe, et al.
Publicado: (2022)

Inhibitory Role of the Small Leucine-Rich Proteoglycan Biglycan in Bladder Cancer
por: Niedworok, Christian, et al.
Publicado: (2013)

Biglycan- and Sphingosine Kinase-1 Signaling Crosstalk Regulates the Synthesis of Macrophage Chemoattractants
por: Hsieh, Louise Tzung-Harn, et al.
Publicado: (2017)

Biglycan: A Multivalent Proteoglycan Providing Structure and Signals
por: Nastase, Madalina V., et al.
Publicado: (2012)

Biglycan expression and its function in human ligamentum flavum
por: Salimi, Hamidullah, et al.
Publicado: (2021)

Granzyme B Cleaves Decorin, Biglycan and Soluble Betaglycan, Releasing Active Transforming Growth Factor-β1
por: Boivin, Wendy A., et al.
Publicado: (2012)

Glutamine Deprivation Induces Abortive S-Phase Rescued by Deoxyribonucleotides in K-Ras Transformed Fibroblasts
por: Gaglio, Daniela, et al.
Publicado: (2009)

Targeting K-Ras and apoptosis-driven cellular transformation in cancer
por: Godwin, Isha, et al.
Publicado: (2021)

Correction: Granzyme B Cleaves Decorin, Biglycan and Soluble Betaglycan, Releasing Active Transforming Growth Factor-β1
por: Boivin, Wendy A., et al.
Publicado: (2012)

Soluble biglycan: a potential mediator of cartilage degradation in osteoarthritis
por: Barreto, Goncalo, et al.
Publicado: (2015)

Decorin knockdown is beneficial for aged tendons in the presence of biglycan expression
por: Beach, Zakary M., et al.
Publicado: (2022)

Involvement of Autophagy in Oncogenic K-Ras-induced Malignant Cell Transformation
por: Kim, Min-Jung, et al.
Publicado: (2011)

Activation of K-RAS by co-mutation of codons 19 and 20 is transforming
por: Naguib, Adam, et al.
Publicado: (2011)

Biglycan enhances gastric cancer invasion by activating FAK signaling pathway
por: Hu, Lei, et al.
Publicado: (2014)

Biglycan fragmentation in pathologies associated with extracellular matrix remodeling by matrix metalloproteinases
por: Genovese, Federica, et al.
Publicado: (2013)

Identification of the effector domain of biglycan that facilitates BMP-2 osteogenic function
por: Jongwattanapisan, Prapaporn, et al.
Publicado: (2018)

Biglycan as a potential diagnostic and prognostic biomarker in multiple human cancers
por: Zhao, Shou-Feng, et al.
Publicado: (2020)

Serum Decorin, Biglycan, and Extracellular Matrix Component Expression in Preterm Birth
por: Mennella, Jenna M., et al.
Publicado: (2020)

Identification and Validation of Biglycan as Prognosis and Therapy Markers for Patients with Stomach Adenocarcinoma
por: Shao, Changming, et al.
Publicado: (2021)

IPSC reprogramming of two patients with spondyloepimetaphyseal dysplasia (SEMD, biglycan type)
por: De Kinderen, Pauline, et al.
Publicado: (2023)

Biglycan and reduced glycolysis are associated with breast cancer cell dormancy in the brain
por: Sunderland, Ashley, et al.
Publicado: (2023)

Relevance of 2′-O-Methylation and Pseudouridylation for the Malignant Melanoma
por: Jasinski-Bergner, Simon, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_o3rsls1mjnm7l770gta889gj3k