The African swine fever virus protease pS273R inhibits DNA sensing cGAS-STING pathway by targeting IKKε

African swine fever virus (ASFV), a large and complex cytoplasmic double-stranded DNA virus, has developed multiple strategies to evade the antiviral innate immune responses. Cytosolic DNA arising from invading ASFV is mainly detected by the cyclic GMP-AMP synthase (cGAS) and then triggers a series...

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Detalles Bibliográficos
Autores principales: Luo, Jia, Zhang, Jiajia, Ni, Jinghua, Jiang, Sen, Xia, Nengwen, Guo, Yiwen, Shao, Qi, Cao, Qi, Zheng, Wanglong, Chen, Nanhua, Zhang, Quan, Chen, Hongjun, Chen, Qing, Zhu, Hongfei, Meurens, François, Zhu, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9067533/
https://www.ncbi.nlm.nih.gov/pubmed/35437104
http://dx.doi.org/10.1080/21505594.2022.2065962

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